Braf^tm1Wds

LoxP sites were inserted to flank exon 3 according to nomenclature in J:29234. An FRT-flanked neomycin resistance cassette was removed prior to ES cell injection. Deletion of exon 3 would cause a reading frame shift and introduce a translational stop codon at position 132, truncating the RBD, CRD and kinase domains. (J:121660)