这些小鼠表达来自ROSA启动子的人类滑膜肉瘤融合基因,18号染色体与EGFP二顺式转录单位(IRES-EGFP)的bicistronic mRNA。载体中还包含一个强的转录终止信号NeoPA,前后由loxP位点标记,这样在没有Cre重组酶存在的情况下,插入的cDNA不会被转录。来源:(J:120967)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
--
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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