这个转基因构建包含小鼠albumin启动子,驱动murine F5(FV)基因的表达,包括整个编码序列。在F5基因编码序列之后插入了带有细菌基因的IRESEGFPR cassette。在F5 cDNA前方引入了优化的剪接信号的嵌合内含子,以增强基因表达。F5的表达仅限于肝脏,而EGFP的表达未检测到。(来源:J:86150)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F1 or C57BL/6 x (C57BL/6 x SJL)F1
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插入
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1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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