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中文
一项包含插入HPRT cassette到第五内含子，随后移除，以及再插入第二个HPRT cassette到第三内含子的多步骤靶向过程，实现了4-5号外显子两侧带有loxP位点的标记。短暂的Cre表达最终切除了这两个外显子和第二个HPRT cassette。Northern blot和Western blot分别验证了突变体中转录本和蛋白质的缺失。(来源：J:120105)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
