在exon 1的5'端插入了floxed的诺姆西林筛选 cassette,随后在 intron 1内插入了第三个loxP位点。这与创建Fstl3tm1Alsc的同一种靶向事件一致。随后与携带cre表达转录因子的 mice杂交,导致诺姆西林筛选 cassette被剔除,留下loxP位点位于exon 1的两侧。(来源:J:119526)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
插入
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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