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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Slc6a3
tm1(cre)Lrsn
Alias:
DAT-cre
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基础信息
表型特征
文献报道
将Cre重组酶的cDNA和含FRT标记的新 cassette插入了第2外显子。与在生殖细胞中表达FLP重组酶的 mice杂交后,移除了neo。这些 mice在中脑的黑质多巴胺神经元中表达Cre重组酶。(来源:J:119515)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3702746
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
4
62
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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