这个转基因载体包含Notch1细胞内域,位于鸡β-actin启动子(CAG启动子)下游,以及一个被Cre介导剪切掉的氯胺酮甲酰基转移酶基因(cat,作为填充序列)。当cat基因被Cre激活时,修饰的等位基因在Cre表达的组织中表达Notch1。(来源:J:108444)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x C3H)F1
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插入
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1
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4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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