插入的转基因包含一个1.1kb的Eno2启动子区域片段,驱动一个带有核定位信号的Cre阅读框。该转基因在发育和成年大脑中表达。在9.5-13.5天的胚胎期,重组酶活性在前脑、后脑和中脑弯曲处检测到。在成年大脑中,重组酶活性出现在大脑皮层、小脑、海马、皮层和丘脑区域。(来源:J:73147)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
CBA x C57BL/6
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插入
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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