A rearranged mouse TCR Vbeta4-Dbeta-Jbeta2.6 genomic clone was derived from a T helper cell clone (3A) specific for nucleosomes and its immunodominant histone peptide H4 (71- 94). Eighty to ninety percent of CD4 T cells express the transgenic TCR. (J:119333, J:119334, J:119335)