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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Nts
tm1Mom
Alias:
NT-GFP
Neurotensin-IRES-tauGFP
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基础信息
表型特征
文献报道
在终止密码子后3个碱基的位置插入了IRES-tauGFP和一个由loxP标记的pgk-neomycin cassette。之后通过Cre介导的重组方式移除了neo cassette。Nts和tauGFP都得到了表达。(来源:J:116039)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3695392
129P2/OlaHsd
Targeted
插入
--
1
--
2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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