这种突变在BALB/cHeA小鼠中被发现。Southern blot分析未检测到基因的任何缺失、插入或重排。然而,对棕色脂肪来源的RNA进行的Northern blot分析显示,转录本水平减少了50倍,并且这种转录本的大小发生了改变。 (Source: The mutation was detected in BALB/cHeA mice. Southern blot analysis failed to detect any deletions, insertions, or rearrangements of the gene. Northern blot analysis on RNA from brown fat revealed a 50-fold decrease in transcript abundance with an altered transcript size.)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
BALB/cHeA
Spontaneous
未定义
--
1
2
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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