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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Tnf
tm3Gkl
Alias:
TNF
delta1-12
Tnf
tm
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基础信息
表型特征
文献报道
一段724bp的序列,包含第二和第三外显子,被替换为一个511bp的突变片段,缺失了前12个溶质TNF的氨基酸,之后neo标记被移除。(来源:J:114740)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3692522
129S/SvEv-Gpi1c
Targeted
插入,基因内删除
--
1
3
5
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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