1-3外显子,包含转录和起始翻译点,以及整个BH3域,被替换为neo。 Western blot和实时PCR确认了造血细胞中无表达(来源:J:115660)
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Exons 1-3, which contain the transcription and translation start sites and the entire BH3 domain were replaced by a neo. Western blot and real-time PCR confirmed absence of expression in hematopoietic cells. (J:115660)