使用了一个替代载体,插入了包含:一个带有所有三个阅读框终止密码子的SpeI连接器,一个与lacZ报告基因融合的反式病毒内源性启动子元件(IRES)带有3'的polyA信号,以及hygromycin基因,目标位于Il5基因的第三外显子中的位点。(来源:J:113543)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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