在该位置插入了一个带有IRES-eGFP元件和编码含有两条丝氨酸替换为 glutamate 的Ikbkb激酶域活化环的cDNA序列,前有floxed stop-neo cassette,Ikbkb的表达将由ROSA26内源性启动子控制,经Cre介导的STOP cassette切除后。 (来源:J:113365)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6.Cg-Thy1a
Targeted
插入
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42

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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