8号和9号外显子周围有loxP位点,通过同源重组,插入了一个带有loxP位点的neo抗性基因座,它位于可敲除的外显子下游。通过与CMV-Cre转基因小鼠杂交,移除了neo基因座(来源:J:111787)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1+
Targeted
插入
--
1
15
22

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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