在Klhl1的转录起始位点插入了LoxP位点,这同时也位于Klhl1polyA信号上游区域。随后,一个由2个FRT和1个3'LoxP标记的neo cassette被插入到Klhl1的第一个内含子中,这个内含子位于Klhl1as的转录起始点之后。与能产生FLP的转基因小鼠杂交后,neo cassette被移除,使得Klhl1的exon 1被LoxP位点包裹。(来源:J:112937)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
插入
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部