通过Cre介导的重组,去除了10-13号外显子。这些外显子编码膜蛋白区域和部分细胞内域。 Western blot在突变体中未能检测到蛋白。这个等位基因来源于Pirbtm1Stz(来源:J:112843)。
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Cre-mediated recombination was used to remove exons 10-13. These exons encode the transmembrane domain and part of the intracellular domain. Western blot failed to detect protein in mutants. This allele was generated from Pirbtm1Stz. (J:112843)