设计了一种向 intron 4 插入一个带有 floxed neo 的向量,同时在 intron 7 内加入第三个 loxP 立场。在生殖细胞中 Cre 表达导致了 exons 5-7 的剔除。(来源:J:111416)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
基因内删除
--
1
--
15

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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