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中文
设计了一个靶向载体，目标是将酪氨酸499替换为苯丙氨酸（Y499F），并插入第13号外显子的终止子。载体中包含了一个IRE-Sneomycin序列。RT-PCR证实了突变序列。 Western blot检测到了该位点产生的两种异构体水平的降低。（来源：J:111432）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
