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中文
设计了一个靶向载体，通过在exon 1内插入IRES-betagal-MC1-neo来使该位点失活。betagal的表达原本会受到内源性启动子的调控，但并未检测到表达。RT-PCR没有检测到exon 1的野生型转录本。对突变体的蛋白质分析也未发现免疫反应。(来源：J:111359)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
