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中文
设计了一个PGK-neo载体，用于替换编码区域1499-1861（对应exons 14-16）的序列。分析显示neo cassette被剪接出来了。生成的转录本产生了一个在框架内的126个氨基酸的缺失，位于催化域的N端，这个区域包含两个二价锌结合位点。由于缺失是同框的，可以产生一个大约75kDa的突变蛋白。(来源：J:111662)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
