在基因中插入了一个LacZ-neomycin cassette,由内源性基因启动子驱动β-半乳糖苷酶的表达。所有分析的组织中都检测到了RNA转录。大部分检测的组织中都发现了LacZ表达,特别是在神经系统和肺部。淋巴结、主动脉、肝脏和胰腺中未检测到LacZ表达。(来源:J:101679)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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