在基因中插入了一个LacZ-neomycin cassette,由内源性基因启动子驱动β-半乳糖苷酶的表达。基因表达分析证实了前额叶、纹状体、海马和肾上腺不表达。LacZ表达在肾脏、输尿管、肾上腺、睾丸、前列腺和子宫中检测到。(来源:J:101679, J:194189)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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