人类的GFAP启动子被用来驱动Cre重组酶的表达,带有来自小鼠protamine-1基因的内含子和polyadenylation信号。这个启动子-Cre片段被四个基因组绝缘子的拷贝包裹。Cre重组酶的表达仅限于大脑中的GFAP阳性星形胶质细胞,而不表达在神经元和少突胶质细胞中。(来源:J:108621)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x C3H
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25

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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