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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Aqp2
tm1Bxy
Alias:
Aqp2
flox
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基础信息
表型特征
文献报道
设计了一个靶向载体,其包含-loxP位点以定位在exon 2外。载体中插入了PGK-neo,当Cre重组酶表达时,它会随着exon 2一起被剔除。(来源:J:110648)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3653759
C57BL/6J x (Rb(11.16)2H x Rb(16.17)32Lub)F1
Targeted
插入
--
1
3
2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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