A neomycin resistance cassette was inserted to replace part of exons 25 and 28 and all of exons 26 and 27. The targeted sequence encoded amino acids 1053-1230, common to all isoforms. (J:110693)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count