在通过同源重组在Hira基因中插入了loxP位点的ES细胞系中,通过逆转录病毒将第二个loxP位点插入了T10基因。短暂的Cre表达在这些ES细胞中导致T10至Hira区域大约1MB的区域被删除。(来源:J:67409)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
Intergenic deletion, Intragenic deletion
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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