Del(16T10-Hira)4Bld

In an ES cell line in which a loxP site previously had been inserted into the Hira gene by homologous recombination, a second loxP site was inserted into the T10 gene using a retrovirus. Transient cre-expression in the ES cells resulted in deletion of a ~ 1Mb region from T10 to Hira. (J:67409)