一种包含Hprt3'选择 cassette和LoxP位点的靶向载体替换了Es2el基因的200bp包含exon 4的片段。在来自AB2.2 ES细胞的双靶向细胞系217中,通过这种替换生成了Es2eltm1Bld突变基因型。(J:57757)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
插入,基因内删除
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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