使用了带有Hprt delta5' cassette和LoxP位点的靶向载体,来替换Ufd1l基因的2-3号外显子,形成了Ufd1ltm1Bld突变型杂合子。这个突变体是在最初从AB2.2 ES细胞系衍生出的217号双靶细胞中创建的,参考文献为J:57757。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
基因内删除
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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