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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Hpn
tm1Qwu
Alias:
Tmprss1
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基础信息
表型特征
文献报道
删除了编码保守激活部位和大部分催化区域的5-8外显子,并用诺卡因选择标记片段替换。通过对突变小鼠肝脏总RNA的Northern blot分析显示,这个等位基因没有检测到可识别的转录本。(来源:J:45393)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3639336
129X1/SvJ
Targeted
插入,基因内删除
--
1
--
6
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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