鸡骨骼肌α-肌动蛋白基因的近端启动子区域,加上首内含子和3'非编码区的1.8千碱基,指导了人类胰岛素样生长因子1(IGF1)的表达。转基因小鼠体内携带单拷贝的转基因,只在横纹肌中表达,并且在骨骼肌中的含量高于心脏。骨骼肌中IGF1的浓度提高了47倍。(来源:J:25522)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB
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插入
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1
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7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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