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中文
将绿色荧光蛋白(GFP)的cDNA插入到第一个外显子，使得内源性启动子驱动GFP的表达。在克隆小鼠产生前，通过Cre介导的重组方式移除了邻近的选择性标记。GFP的表达在时间和空间上都模拟了内源性Il2基因的表达，实验证明，GFP的激活也由类似内源基因的共刺激信号触发。(来源：J:49411)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
