Cre重组酶的表达导致了exon 5的去除,这个exon编码了C端的锌指结构域。 Western blot没有在突变体中检测到预期大小的稳定蛋白。(来源:J:108963)
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Cre recombinase expression resulted in the removal of exon 5, which encodes the C-terminal zinc finger domain. Western blot did not detect a stable protein of expected size from mutants. (J:108963)