一种包含转录接头序列、内源性核糖体进入位点、可选择性颜色指示标记、β-geo和polyA序列的基因陷阱载体被插入到了该基因座的第13个内含子中。反转录PCR在突变大脑中证实了融合转录本的表达,但表达水平明显低于野生型小鼠。(来源:J:108880)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S5/SvEvBrd
Gene trapped
基因捕获载体的插入
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1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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