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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Slc6a4
Gt1(IRESBetageo)lLex
Alias:
5-HTT
-
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基础信息
表型特征
文献报道
一种包含转录接头序列、内源性核糖体进入位点、可选择性颜色指示标记、β-geo和polyA序列的基因陷阱载体被插入到了该基因座的第13个内含子中。反转录PCR在突变大脑中证实了融合转录本的表达,但表达水平明显低于野生型小鼠。(来源:J:108880)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3628526
129S5/SvEvBrd
Gene trapped
基因捕获载体的插入
--
1
2
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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