Solitaire小鼠表现出与Mayday小鼠相同的表型,Mayday小鼠带有Kcnj8基因的突变。尽管它们来自不同的遗传背景,但补救测试表明Solitaire与Mayday是等同的基因。基因测序结果显示,Solitaire突变等同于Mayday突变。Kcnj8基因的突变包括1号外显子和大部分2号外显子的缺失,因为它们被2号内含子的倒置片段所取代。(引用文献:J:88776, J:126658)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Chemically induced
Intragenic deletion, Inversion
隐性
1
3
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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