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中文
设计了一个靶向载体，用于替换8号染色体上编码PKR活化域的约500bp序列，替换成抗氨苄青霉素的耐药基因座。没有表达出截短的蛋白质。突变的杂交mRNA被证明包含1-22个基本地质序列、内含子7、923-934段中断的8号外显子以及整个新基因座。(来源：J:108297)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
