将含有6.121 VHDHJH抗体特异序列和一个-loxP引导的诺卡因抗性基因座的靶向载体插入到JH区域,替换后通过Cre介导的重组,在雄性嵌合小鼠传递时去除了诺卡因基因座。(J:107241)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S4/SvJae-Tg(Prm-cre)70Og
Targeted
Insertion, Intergenic deletion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部