将含有6.121抗体VκJk序列的靶向载体插入到Jk区域,替换该区域后,通过Cre介导的重组,在杂交雄性小鼠传递时,Neomycin cassette被删除了(来源:J:107241)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S4/SvJae-Tg(Prm-cre)70Og
Targeted
插入
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--
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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