(尼古丁抗性基因 cassette 替换了exon 1开头的39个氨基酸序列,以及exon 2和exon 3的全部编码区域。 Western blot 检测确认了没有基因产物产生。(来源:J:109145))
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A neomycin resistance cassette replaced the coding sequence for the N-terminal 39 amino acids from exon 1 as well as all of exon 2 and exon 3. Western blot analysis confirmed the absence of gene product. (J:109145)