一个靶向构建被用来去除编码六个多巴胺的序列以及两个"PXXP"结构(包括p.E75_S91del)。对突变体和野生型基因组的mRNA进行定量分析显示,两者的转录活动相同。(来源:J:108183)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae-Tg(Prm-cre)70Og
Targeted
基因内删除
--
1
65
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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