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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Trp53
tm3Wahl
Alias:
p53
deltaP
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基础信息
表型特征
文献报道
一个靶向构建被用来去除编码六个多巴胺的序列以及两个"PXXP"结构(包括p.E75_S91del)。对突变体和野生型基因组的mRNA进行定量分析显示,两者的转录活动相同。(来源:J:108183)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3624429
129S4/SvJae-Tg(Prm-cre)70Og
Targeted
基因内删除
--
1
65
5
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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