通过暂时的Cre表达,Exon 1在ES细胞中被去除。 Western blot结果显示,突变型ES细胞中主要的野生型蛋白缺失了(来源:J:92066)
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Exon 1 was removed via transient cre expression in ES cells. Western blot analysis shows that the predominant wild-type protein was absent in mutant ES cells. (J:92066)