设计了一种靶向载体,用于替换包含起始密码子和周围内含子区域的序列,替换成诺卡因抗性基因。RT-PCR结果显示突变体中无转录本。 Western blot结果显示无野生型蛋白质,但无法确定是否缺少C端截短的蛋白质。(来源:J:106931)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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