包含lacZ基因和一个由loxP位点标记的PGKneo cassette的靶向载体,它突变了exon 2的一部分,包括起始密码子,exons 3到6的全部,以及exon 7的部分。对纯合突变小鼠睾丸的RT-PCR分析未检测到转录本。(来源:J:102875)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
--
25

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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