由Cre介导的重组导致了从子家族A1到第三个共有的外显子的protocadherin gamma基因座的缺失。通过使用针对protocadherin gamma共显子的探针进行的Northern blot实验证实了突变体中转录本的完全丢失。蛋白质缺失通过Western blot分析得到了确认。(来源:J:107735)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
基因间区删除
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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