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中文
在exon 22的两侧插入了LoxP位点，这个exon编码了RNA酶III域的大部分。丢失这个exon会导致因插入突变产生的框移终止密码子，可能使转录本稳定性下降。通过Flp介导的重组，移除了载体中包含的FRT标记的neo序列。(来源：J:106792)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
