这个转基因包含了Epstein-Barr病毒主要潜伏期C启动子(Cp)的CBF1/RBPSUH结合位点的四个串联拷贝,后面跟着SV40的最小启动子和绿色荧光蛋白的编码序列。当Notch信号通路激活时,携带这种转基因的小鼠细胞会表达绿色荧光蛋白。(来源:J:96367)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x SJL/J)F2
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45

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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