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中文
在exon 1上游插入了一个loxP位点，然后在内含子2中插入了一个loxP标记的nemoycin/thymidine kinase筛选元件。在ES细胞中短暂的Cre表达导致了包括exons 1-2和筛选元件在内的所有间隔序列的消除。杂合子小鼠在肝脏和乳腺中显示了蛋白质活性的降低。(来源：J:59695)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
