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中文
这个转基因包含了小鼠α肌动蛋白重链(Myh6)的启动子和一个 pik3ca( pik3rl, p85)结合区域缺失了催化域的突变p110。Myh6驱动心肌细胞中 pik3ca 的非同源等位基因表达。免疫沉淀和 Western blot 验证了转基因在心脏中的特异性表达。脂质磷酸化酶激酶的活性检测显示，其活性降低了77% (来源：J:62707)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
