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中文
这个转基因包含了小鼠α肌动蛋白重链(Myh6)的启动子和 pik3r1( pik3ca 的p85)的iSH2域，两者通过N端连接在牛PIK3CA(p110alpha)的前端。Myh6驱动心肌细胞中特异性表达一个持续活跃的磷脂酰肌醇-3-激酶。免疫沉淀和western blot确认了转基因在心脏中的表达，而脂质激酶实验显示了磷脂酰肌醇-3-激酶活性增加了6.5倍。(来源：J:62707)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
